ALFRED BENNUN, PH.D.

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The relation of the light-dependent and light-triggered adenosine triphosphatases to photophosphorylation
Bennun, A. and Avron, M.


1. Wide specificity for nucleoside triphosphates was found for light-dependent and light-triggered ATPase (ATP phosphohydrolase, EC 3.6.1.3) of isolated chloro¬plasts.
2. The reported wide specificity of photophosphorylation for nucleoside di-phosphates has been confirmed under more rigorous conditions. Similar wide specificity was found for the same compounds as inhibitors of the light-requiring ATPases.
3. The affinity of photophosphorylation for ADP and GDP was found to be similar under conditions optimal for photophosphorylation, but very different under conditions optimal for the light-requiring ATPases.
4. The affinity of the light-requiring ATPases for ADP and GDP as competitive inhibitors was found to be identical to the affinity of photophosphorylation for the compounds under the same experimental conditions.
5. Several inhibitors acted similarly on the light-requiring ATPases and on photophosphorylation.
6. A coupling factor, previously reported to be essential for photophosphory¬lation, was found to be essential also for the light-requiring ATPases.
7. It is suggested that the evidence presented strongly supports the hypothesis that the light-requiring ATPases of chloroplasts share part of the energy-transport path used for ATP production during photophosphorylation.


Biochimica et Biophysica Acta, 109, (1965), 117-127